HRT and breast cancer

Breast Implants and Breast Cancer

HRT: some unresolved clinical issues in breast cancer, endometrial cancer and premature ovarian insufficiency.

Many important issues regarding HRT and the management of postmenopausal women are unresolved and require ongoing consideration and some explanation. HRT is only one of many factors affecting the risk of breast cancer and the risk of breast cancer is not increased in past users of HRT. There is seemingly a paradox in the effect of body weight and HRT on breast cancer risk. It is unclear whether...

Breast Cancer and Screening

سرطان پستان یکی از شایع ترین بیماریهای بدخیم و اولین علت مرگ و میر زنان بوده و تقریبا یک سوم تمام سرطانهای زنان را تشکیل می دهد.

HRT, breast and endometrial cancers: strategies and intervention options.

The demand for hormone replacement therapy (HRT) by women who enter the menopause is rapidly increasing in all developed countries. The concern that HRT may enhance morbidity and mortality from malignant diseases still limits the widespread adoption of hormonal treatments. Overall, epidemiological data on cancer incidence and HRT are reassuring, although long-term or inappropriate therapies may...

MTHFR polymorphisms, diet, HRT, and breast cancer risk: the multiethnic cohort study.

Methylenetetrahydrofolate reductase (MTHFR) is a key regulatory enzyme in the metabolism of folate, a nutrient which has recently been found to be inversely related to breast cancer in women who drink alcohol. Two common variants in the MTHFR gene (C677T and A1298C) have been associated with a reduced activity of this enzyme, thereby increasing the availability of folate for thymidylate and pur...